I am an Assistant Professor at the Department of Applied Mechanics, Biomedical Engineering at IIT Madras. My research interests are in the field of biological applications of nanomaterials, drug Delivery, and biophysics. My group is currently working on different streams including Space Medicine, Developing nanotherapeutics for Cancer, studying nanomechanics of proteins, and development of biosensors for disease diagnosis
Total number of
publications: 35; Aggregate impact factor: 227.185; Total number of citations:
389; h-index :9; i10 index:9
1. Narendran Sekar, Pushpkant Sahu, Swathi Sudhakar*, Hema Chandra
Kotamarthi*, "Electrostatic interactions drive phase separation in Pup
protein." RSC Chemical Communications 2024, 60,
14980-14983. Impact factor: 4.3.
2. Anisha Kabir, Mukilarasi B, Anagha Manohar, Vimalraj S* and Swathi
Sudhakar*, “Protein bioactive complexes promote osteogenesis under a
microgravity environment” International Journal of Biological
Macromolecules. (Accepted) Impact factor: 7.7
3. Vimalraj Selvaraj, Swathi Sudhakar, S Sekaran, et al.,
“Cutting-edge nanotechnology transforming cancer surgery and recovery”. International
Journal of Surgery, 2024,10 (12), 8207-8209. Impact factor: 12.5
4. Thilak
Raj, Srestha Roy, Ashwin Kumar, Basudev Roy*, Ethayaraja Mani, Swathi
Sudhakar*, "Direct measurement of
self-diffusiophoretic force generated by active colloids of different patch
coverage using optical tweezers." Journal of Colloid and Interface
Science 677 2025, 986-996. Impact factor: 9.4
5. Anisha Kabir, Vimalraj Selvaraj*, Swathi Sudhakar*, "Protein
Nano Coop Complexes Promote Fracture Healing and Bone Regeneration in a
Zebrafish Osteoporosis Model." Biomacromolecules 2024,25
(11), 7237-7248. Impact factor: 5.5
6. El Sherkawi T, Swathi S, Singh SK, Gupta G,
Paudel KR, Hansbro PM, Oliver B, De Rubis G, Dua K. "Therapeutic potential of 18-β-glycyrrhetinic acid-loaded poly
(lactic-co-glycolic acid) nanoparticles on cigarette smoke-induced in-vitro
model of COPD." Pathology-Research and Practice, 2024, 263,155629.
Impact factor: 2.9
7. Srisowmeya
G, Bhagyasri Bharathi R, Swathi Sudhakar, Ethayaraja Mani. "Development of Hematite Nano Ellipsoids/Pectin Composite Films
for Green Packaging Applications." Langmuir 40.35 (2024):
18418-18429. Impact factor: 3.7
8. Jey
Kumar P, Manali P, Parkshit R, Imrankhan N, Raagul S, Swathi S,
Jeyaprakash M R, V V Satyanarayana Reddy, Jayakumar V, Priti M, Sudhakar K,
Indhumati T, Gowthamarajan K, "A review of the
physiological effects of microgravity and innovative formulation for space
travelers." Journal of Pharmacokinetics and Pharmacodynamics, 2024,1-16.
Impact factor: 2.2
9. Lele
S, Satwik M, Ziruo L, Ruitong D, Thilakraj K, Swathi Sudhakar, Saji
George, "Nanomaterials enhanced the
antimicrobial effect of microwave treatment: understanding the role of
nanomaterial properties." Journal of Nanoparticle Research, 2024,
26 (8), 195. Impact factor: 2.1
10. Asuwin
Prabu R G, Anagha Manohar, Narendran S, Anisha Kabir, Swathi Sudhakar*, "Effect of Simulated Microgravity on Artificial Single Cell
Membrane Mechanics." Microgravity Science and Technology,
2024, 36(4) 47. Impact factor: 1.3
11. Subastri
Ariraman, Abirami S, Kaviya VB, Swathi Sudhakar*, "Quercetin-loaded nanoarchaeosomes for breast cancer therapy: a
ROS mediated cell death mechanism." Materials Advances,2024, 5
(17): 6944-6956. Impact factor: 5.2
12. Anagha
Manohar, MG Basavaraj, Swathi Sudhakar, Ethayaraja Mani*, "Drying-Induced Flash Nanoprecipitation in a Sessile Drop: A
Route to Synthesize Polymeric Nanoparticles." Langmuir 2024,
40 (26), 13613–13621. Impact factor: 3.7
13. Sameer
S, Kaviya VB, Anisha Kabir, Thilak Raj, and Swathi Sudhakar*, "Microgravity as a platform to enhance drug loading efficiency in
nanomaterials." Journal of Drug Delivery Science and Technology 2024,
98, 105869. Impact factor: 4.5
14. Gabriele
De Rubis, Keshav Raj Paudel, Stewart Yeung, Siddiq Mohamad, Swathi Sudhakar,
Brain Gregory George oliver, Kamal Dua, "18-β-glycyrrhetinic
acid-loaded polymeric nanoparticles attenuate cigarette smoke-induced markers
of impaired antiviral response in vitro." Pathology-Research and
Practice, 2024, 257,155295. Impact factor: 2.9
15. TR Akshaya, Swathi Sudhakar, Ethayaraja Mani, K
Murali, "Effect of biopolymer concentration on
the kinetics of marine snow formation." Deep Sea Research Part I:
Oceanographic Research Papers, 2024, 207,104291. Impact factor: 2.3
16.
Abhishek Sasmal, Abirami
Seetharaman, Payel Maiti, Swathi Sudhakar, A Arockiarajan "Charge-defect tuned PVDF based ternary biocompatible composite as
skin touch actuated single-electrode triboelectric nanogenerator for wireless
healthcare monitoring." Chemical Engineering Journal, 2024, 487,
150573. Impact factor: 13.4
17.
Selvaraj Vimalraj, Dharunya Govindarajan, Swathi
Sudhakar, Renugaa Suresh, Praveenkumar Palanivel, Saravanan Sekaran,"Chitosan
derived chito-oligosaccharides promote osteoblast differentiation and offer
anti-osteoporotic potential: Molecular and morphological evidence from a
zebrafish model." International Journal of Biological
Macromolecules 2024, 259, 129250. Impact factor: 7.7
18.
Vimalraj Selvaraj, Swathi
Sudhakar, Saravanan Sekaran, Suresh Kumar Rs,
"Enhancing precision and efficiency: harnessing robotics and artificial
intelligence for endoscopic and surgical advancements." International
Journal of Surgery, 2024, 110 (2), 1315-1316. Impact factor: 12.5
19. Kaviya
VB, Thilak Raj, Abirami S, Subastri S, Swathi Sudhakar*, "Elucidating shape-mediated drug carrier mechanics of hematite
nanomaterials for breast cancer therapeutics." Journal of
Materials Chemistry B 2024, 12 (20), 4843-4853. Impact factor: 6.1
20. Kaviya
VB, Abirami S, Subastri S, Poornima BS, Natasha P, Julia S, Swathi S*, . "Doxorubicin loaded thermostable nanoarchaeosomes: a
next-generation drug carrier for breast cancer therapeutics." Nanoscale
Advances 2024, 6 (8), 2026-2037. Impact factor: 4.6
21.
D Govindarajan, S Saravanan, Swathi
Sudhakar, S Vimalraj."Graphene: A Multifaceted Carbon-Based Material
for Bone Tissue Engineering Applications." ACS omega, 2023, 9
(1), 67-80. Impact factor: 3.7
22. Swathi Sudhakar, Anagha Manohar, and
Ethayaraja Mani. "Liquid–liquid phase separation (llps)-driven
fibrilization of amyloid-β protein." ACS Chemical Neuroscience, 2023, 14
(19), 3655-3664.
Impact factor:
4.2
23. Sourabh C, Leander C, Mahesh H, Sukriti V, Rajan K, Faisal A, Mohammed
Javed A, Zia ur Rehman, Omji P, Rubiya Khursheed, Vancha H, Gaurav G, Bimlesh
K, Pankaj K, Kuppusamy G, Anindita De, Swathi Sudhakar, Umashankar M S,
Monica Gulati, Kamal Dua, Sachin K, "Quality by design-oriented
formulation optimization and characterization of guar gum-pectin based oral
colon targeted liquisolid formulation of xanthohumol." Journal of
Drug Delivery Science and Technology, 2023, 82, 104350. Impact
factor: 4.5
24. Alexandra
Ciorîta, Michael Bugiel, Swathi Sudhakar, Erik Schäffer, and Anita
Jannasch"Single depolymerizing and transport
kinesins stabilize microtubule ends." Cytoskeleton, 2021, 78 (5),
177-184. Impact factor: 2.4
25. Sriram Krishnamurthy, Swathi Sudhakar, and Ethayaraja Mani.
"Kinetics of aggregation of amyloid β under different shearing conditions:
Experimental and modeling analyses." Colloids and Surfaces B:
Biointerfaces, 2022, 209, 112156. Impact factor: 5.4
26. Akanksha
Dohare*, Swathi Sudhakar*, Björn Brodbeck, Ashutosh Mukherjee, Marc
Brecht, Andreas Kandelbauer, Erik Schäffer, Hermann A Mayer"Anisotropic and Amphiphilic Mesoporous Core–Shell Silica
Microparticles Provide Chemically Selective Environments for Simultaneous
Delivery of Curcumin and Quercetin." Langmuir, 2021, 37 (45),
13460-13470. Impact factor: 3.7
27. Swathi Sudhakar, Mohammad Kazem, et al.
"Germanium nanospheres for ultra resolution pico tensiometry of kinesin
motors." Science, 2021, 371 (6530), eabd9944. Impact
factor: 44.8
28. Viktoria
Welder, Fäbian struts, Swathi Sudhakar, Gero Lutz Hermsdorf, York Dieter
Stierhof, Erik Schäffer., "Polycationic gold
nanorods as multipurpose in vitro microtubule markers." Nanoscale
Advances, 2020, 2(9), 4003-4010. Impact factor: 4.6
29. Swathi Sudhakar, Tobias Jörg, et al.
"Supported solid lipid bilayers as a platform for single-molecule force
measurements." Nano Letters, 2019, 19 (12), 8877-8886. Impact
factor: 9.6
30. Swathi Sudhakar, and Ethayaraja Mani.
"Rapid dissolution of amyloid β fibrils by silver nanoplates." Langmuir,
2019, 35 (21), 6962-6970. Impact factor: 3.7
31. Ramesh, Nirmal Kumar, Swathi Sudhakar, and Ethayaraja Mani.
"Modeling of the inhibitory effect of nanoparticles on amyloid β
fibrillation." Langmuir, 2018, 34 (13), 4004-4012. Impact
factor: 3.7
32. Swathi Sudhakar, Poornima Budime
Santhosh, and Ethayaraja Mani. "Dual role of gold nanorods: Inhibition and
dissolution of Aβ fibrils induced by near IR laser." ACS Chemical
Neuroscience, 2017, 8 (10), 2325-2334. Impact factor: 4.2
33. Swathi Sudhakar, Poornima Budime
Santhosh, and Ethayaraja mani. "Role of surface charge of inhibitors on
amyloid beta fibrillation." The Journal of Physical Chemistry C, 2017, 121
(11), 6339-6348. Impact factor: 3.3
34.
Santhosh P. B, Thomas
N, Sudhakar S, Chadha A, Mani E."Phospholipid
stabilized gold nanorods: towards improved colloidal stability and
biocompatibility." Physical Chemistry Chemical Physics, 2017, 19
(28), 18494-18504. Impact factor: 2.9
35.
S. Sudhakar, P.B. Santhosh. Gold Nanomaterials: Recent Advances in Cancer
Theranostics. Advances in Biomembranes and Lipid Self-Assembly, Elsevier,
2017, 01, 003. Impact factor: 8.
BOOK CHAPTER:
1. Advancing In
Vivo Biomedical Research: Design and Implementation of an Affordable
Zebrafish Housing Unit. B. Mukilarasi, S. B. Lakshmi Swarubhaa, A. Natarajan,
S. Swathi, S. Ramakrishnan, S. Saravanan, and S. Vimalraj. Sustainable
Aquaculture
Recent Advances and Techniques. (Forth coming: NOV 2025).
2.
Swathi Sudhakar, Pasupathi Rajendran, and
Erik Schäffer. "Synthesis of Germanium Nanospheres as High-Precision
Optical Tweezers Probes." Optical Tweezers: Methods and Protocols.
New York, NY: Springer US, 2022, 25-35.
3. Sudhakar, S., and P. B. Santhosh. "Gold nanomaterials: recent
advances in cancer theranostics." Advances in Biomembranes and
Lipid Self-Assembly 25 (2017): 161-180.
4.
Thyagarajan, Lakshmi Priya, Swathi Sudhakar,
and Thirumoorthy Meenambal. "Bioremediation of Congo-red dye by using
silver nanoparticles synthesized from Bacillus sps." Bioremediation
and Sustainable Technologies for Cleaner Environment (2017): 119-132.
Patents
1. IDF2918- Swathi Sudhakar, Anish Kabir, Anagha Manohar, Vimalraj S, Anurag Kumar Sinha, Anurag Varma, Maulesh Gadani, Payal Sharma. Zein Nanoparticles Loaded with Antioxidants to Mitigate Oxidative Stress
2. IDF2819- Swathi Sudhakar, Shaik Sameer Basha, Kaviya VB, Anish Kabir, Thilak Raj. Drug loading in nanomaterials using Microgravity.
3. IDF2846- Swathi Sudhakar, Subastri S, Abirami S, and Kaviya VB, Nanoarchaeosomes as novel drug carrier vehicle and methods thereof.
4. IDF3032 Swathi Sudhakar, Vimalraj Selvaraj, Abhishek Sasmal, Arockiarajan Arunachalakasi, Ramakrishnan S, Lakshmi Swarubhaa S B, Meena A, Renuga Suresh Babu. Cobalt Ferric Oxide loaded Halloysite Nanotubes incorporated Nanohydroxyapatite-Sodium Alginate Hydrogel for Bone Tissue Engineering.
5. IDF No 3020. Swathi Sudhakar, Vimalraj Selvaraj, Mukilarasi B, Anisha Kabir, Natarajan A Protein nano coop complexes promote fracture healing and bone regeneration in zebrafish osteoporosis model
6. IDF2985 – Vimalraj Selvaraj, Swathi Sudhakar, Swaminathan Ramakrishnan, Formulation of a composite scaffold for Bone Regeneration using Metalomineral – Loaded Halloysite Nanotubes Incorporated in a Chitosan – Alginate Matrix.
7. IDF2802 – Vimalraj Selvaraj, Swathi Sudhakar, Swaminathan Ramakrishnan, Saravanan Sekaran, A Novel immunomodulatory hydrogel to prevent rejection of allogeneic mesenchymal stem cells.
8. RSA23P0053-IDF-2580. Ethayarajamani, Swathi Sudhakar, Sri Sowmeya G. Biodegradable films for packaging and methods thereof.
9. IDF2803- Vimalraj Selvaraj, Swathi Sudhakar, Swaminathan Ramakrishnan, Saravanan Sekaran, Innovations in Dental Screw Implants for Enhanced Osseointegration.
10. IDF3057.Vimalraj Selvaraj, Swathi Sudhakar, Renugaa Suresh Babu, S. Ramakrishnan. Professor Herbo mineral formulation loaded PCL scaffold for alveolar bone repair.
IDF 3078, Swathi Sudhakar, Arockiarajan A, Sameer S, Vimalraj S, Abhishek Sasmal, Implantable PVDF combinatorial film for multidrug-resistant breast cancer treatment
11. IDF2803- Vimalraj Selvaraj, Swathi Sudhakar, Swaminathan Ramakrishnan, Saravanan Sekaran, Innovations in Dental Screw Implants for Enhanced Osseointegration.
12. IDF 2803, Vimalraj Selvaraj, Swathi Sudhakar, Swaminathan Ramakrishnan, Saravanan Sekaran. Innovations in Dental Screw Implants for Enhanced Osseointegration.
13. IDF 3078, Swathi Sudhakar, Arockiarajan A, Sameer S, Vimalraj S, Abhishek Sasmal, Implantable PVDF combinatorial film for multidrug resistant breast cancer treatment.
14. IDF 3156, Swathi Sudhakar, Ramakrishnan S, Mathana Vetrivel P, Dhaksha Aniesh J, Lateral flow assays-based tuberculosis detection kit.
15. IDF 3200, Swathi Sudhakar, Arockiarajan A, Shaik Sameer Basha, Abhishek Sasmal, Subastri Ariraman, Mukilarasi B, Vimalraj S, "Co-Ni MOF as Drug delivery agent for triple-negative breast cancer.
Professional Recognition/ Award/ Prize/ Certificate,
Fellowship received by the applicant.
Membership and Fellowships of National &
International Academies, and Professional Societies
