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Law of Mobility as diagnositic tool for Diabetes

Diabetic neuropathy is a family of nerve disorders caused by diabetes mellitus (DM). Two-point discrimination (TPD) is used as a tool to evaluate sensory loss in Diabetic Mellitus (DM) subjects. Law of mobility is known but not related to DM subjects. This is a pilot study to relate the Law of mobility for TPD among DM in Indian subjects.

Semmes Weinstein monofilament (SMWF) is used to measure the sensation in the feet. Aesthesiometer was used to find the TPD in hand and leg areas for normal and diabetic subjects and plot the law of mobility.

TPD of normal and diabetic subjects for different areas of hands and legs from proximal to distal was evaluated for 18 subjects. TPD values decrease from proximal to distal areas. Vierodt’s law of mobility holds good for both normal and DM subjects with and without sensation in both hands and holds well in the leg areas for the normal subjects. The law of mobility doesn’t hold good for the DM subjects with and without sensation in leg areas.

TPD in general and law of mobility in particular, is a quantitative and direct measure of sensory loss. The law of mobility holds good for Diabetic subjects without neuropathy but not for patients with neuropathy. Plotting law of mobility for diabetic subjects may provide an easy, cost effective method to evaluate compression neuropathy.

Publications

  1. R. Periyasamy, Manivannan.M, and V.B.Narayanamurthy, "Changes in the Two Point Discrimination and the Law of Mobility in Diabetic Mellitus Patients", Journal of Brachial Plexus and Peripheral Nerve Injury, 3:3, 2008.


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Last Updated: May 26, 2008 4:45 PM Comments: Manivannan M